Jeong-Yoon Kim
  • Ph. D.
  • Jeong-Yoon Kim
  • Biotechnology
  • N11-605
  • Laboratory of Cell Polarity and Aging (N11-605)
  • +82-42-821-6419, 7554

Academic Career

  • B.S., 1984, Seoul National University, Korea
  • M.S., 1986, Seoul National University, Korea
  • Ph.D., 1992, University of California, Davis, USA


  • Post-Doc., 1992-1993, University of California, Davis, USA

Research Interests

  • Cell Polarity

    Prof. Kim is interested in understanding the molecular mechanisms of cell polarity, especially the signaling pathways for the morphogenetic change during cellular differentiation and development.

    • Hippocampal neurons:

      He studies the molecular functions of GEFs or GAPs for Rho GTPases and their regulatory or effector proteins affecting the formation of dendrites or spines in hippocampal neurons.

    • Yeast:

      He also investigates the roles of the NDR kinase (Cbk1) and its downstream effectors in morphogenesis and interaction of Candida albicans with intestinal epithelial cells.

  • Cellular Aging

    Prof. Kim’s research includes the study on the roles of Sirtuin proteins, which belong to a class III histone deacetylase, in cellular aging process.

    • Neuronal stem cells:

      He is keen on investigating the mechanisms by which sirtuins regulate aging of neuronal stem cells.

    • Yeast:

      He has been studying how Sir2 regulates yeast aging process in response to environmental and metabolic stresses and how Sir2 interacts with key kinases, such as TOR and PKA, in nutrient signaling pathways.

Selected Publication

  • Kang WK, Kim YH, Kang HA, Kwon K-S, Kim J.-Y. 2015. Sir2 phosphorylation through cAMP-PKA and CK2 signaling inhibits the lifespan extension activity of Sir2 in Yeast. eLIFE 4: e09709
  • Lee HJ, Kim JM, Kang WK, Yang H, Kim J-Y. 2015. The NDR kinase Cbk1 downregulates the transcriptional repressor Nrg1 through the mRNA-binding protein Ssd1 in Candida albicans. Euk Cell. 14(7): 671-83.
  • Bal J, Lee HJ, Cheon SA, Lee KJ, Oh DB, Kim J.-Y. 2013. Ylpex5 mutation partially suppresses the defective hyphal growth of a Yarrowia lipolytica ceramide synthase mutant, Yllac1, by recovering lipid raft polarization and vacuole morphogenesis. Fungal Genet Biol. 50:1-10.
  • Cheon SA, Bal J, Song Y, Hwang HM, Kim AR, Kang WK, Kang HA, Hannibal-Bach HK, Knudsen J, Ejsing CS, Kim J.-Y. 2012. Distinct roles of two ceramide synthases, CaLag1p and CaLac1p, in the morphogenesis of Candida albicans. Mol Microbiol. 83(4):728-45.
  • Kim J.-Y, Oh MH, Bernard LP, Macara IG, Zhang H. 2011. The RhoG/ELMO1/Dock180 signaling module is required for spine morphogenesis in hippocampal neurons. J Biol Chem. 286(43):37615-24.